HIGH DIAGNOSTIC YIELD OF TARGETED NEXT-GENERATION SEQUENCING IN A COHORT OF PATIENTS WITH CONGENITAL HYPOTHYROIDISM DUE TO DYSHORMONOGENESIS

High Diagnostic Yield of Targeted Next-Generation Sequencing in a Cohort of Patients With Congenital Hypothyroidism Due to Dyshormonogenesis

ObjectiveTo elucidate the molecular cause in a well-characterized cohort of patients with Congenital Hypothyroidism (CH) and Dyshormonogenesis (DH) by using targeted next-generation sequencing (TNGS).Study designWe studied 19 well-characterized patients diagnosed with CH and DH by targeted NGS including genes involved in thyroid hormone production.

read more



The Effect of Using Fluorescent Concretization Intervention on Hand Hygiene Training in Primary School Students

Introduction: Inadequate hand hygiene increases the rates of childhood infectious T-Shirts diseases and deaths, leading to the death of one child per minute.Aim: The aim of the study was to examine the effects of the program in which fluorescent embodiment intervention was used as an educational strategy on the hand washing skills of primary school

read more